Dr. Pawan Kumar Singh

  Hairy Cell Leukemia (HCL) is a rare type of blood cancer that affects the B-cells in the bone marrow. Over the past few years, there have been significant advances in the treatment of HCL, offering new hope and better outcomes for patients. One of the major breakthroughs in treating HCL is the development of targeted therapies. These treatments specifically attack cancer cells without harming normal cells, reducing side effects and improving effectiveness. One such targeted therapy is the drug cladribine, which has shown high success rates in inducing remission. Another promising drug is vemurafenib, particularly effective in patients with a specific genetic mutation (BRAF V600E). In addition to targeted therapies, immunotherapy has emerged as a powerful tool against HCL. Immunotherapy works by boosting the body's natural defences to fight the cancer. Rituximab, an antibody therapy, is often used in combination with other treatments to enhance their efficacy and prolong remission...

  Multiple myeloma is a type of cancer that affects plasma cells in the bone marrow. Living with this condition can be challenging, but with the right coping strategies and support resources, patients can manage their symptoms and maintain a good quality of life. Coping with multiple myeloma begins with understanding the disease and its treatment options. Treatment may include medications, chemotherapy, radiation, and, in some cases, a bone marrow transplant. Staying informed about the latest treatments can help patients make better decisions about their care. For those seeking specialized care, consulting a Bone Marrow Specialist in Gurugram is crucial. Dr. Pawan Kumar Singh, an expert in this field, offers comprehensive treatment plans tailored to each patient’s needs. Managing symptoms and side effects is an important aspect of living with multiple myeloma. Fatigue, pain, and infections are common issues. Patients should communicate openly with their healthcare team to address ...

  Chronic Myeloid Leukemia (CML) is a type of cancer that starts in the bone marrow, where blood cells are produced. It mainly affects adults and progresses slowly, which means it can be managed effectively if detected early. Early detection of CML is crucial. Initially, symptoms might be mild or non-existent. Common early signs include fatigue, night sweats, weight loss, and a feeling of fullness in the abdomen due to an enlarged spleen. Because these symptoms can be vague, they are often overlooked. Regular medical check-ups and blood tests can help detect CML early, even before symptoms become noticeable. Diagnosis of CML typically involves a complete blood count (CBC) to check for abnormal levels of white blood cells. If CML is suspected, a bone marrow biopsy is performed to confirm the diagnosis. Genetic tests are also conducted to identify the presence of the Philadelphia chromosome, a genetic abnormality associated with CML. Modern treatment approaches for CML have sig...

  Chronic Myeloid Leukemia (CML) is a type of cancer that starts in the blood-forming cells of the bone marrow. It primarily affects adults but can occur at any age. Understanding CML, its symptoms, diagnosis, and treatment options is crucial for managing this condition effectively. CML usually progresses slowly and may not show symptoms initially. However, as the disease advances, common symptoms include fatigue, weight loss, night sweats, and an enlarged spleen, which can cause a feeling of fullness or pain in the abdomen. Because these symptoms are quite general, they can easily be mistaken for other illnesses, making early detection challenging.  Diagnosis typically involves a complete blood count (CBC) to check for abnormal levels of white blood cells. If CML is suspected, a bone marrow biopsy is performed to confirm the diagnosis and to determine the stage of the disease. Genetic tests can also identify specific changes in chromosomes that are characteristic of CML. ...

  Acute Myeloid Leukemia (AML) is a type of cancer that starts in the bone marrow, the soft tissue inside bones where blood cells are made. AML progresses quickly and can affect both children and adults. Types of AML AML has several subtypes, which are classified based on the kind of blood cell affected and the changes seen in the cells. The most common types include: Acute Promyelocytic Leukemia (APL) Acute Monocytic Leukemia Acute Myelomonocytic Leukemia Signs and Symptoms AML symptoms can appear suddenly and may include: Fatigue and Weakness: Feeling extremely tired and weak without a clear reason. Frequent Infections: Having infections more often because of low white blood cell counts. Bruising and Bleeding Easily: Getting bruises from minor bumps or bleeding from gums and nose. Shortness of Breath: Feeling breathless, especially after light activities. Bone Pain: Experiencing pain in bones or joints. Diagnosis Diagnosing AML involves several steps: Physical Exam and Medical Hi...